Lophophora fricii

Lophophora fricii
Scientific classification Edit this classification
Kingdom: Plantae
Clade: Embryophytes
Clade: Tracheophytes
Clade: Angiosperms
Clade: Eudicots
Order: Caryophyllales
Family: Cactaceae
Subfamily: Cactoideae
Genus: Lophophora
Species:
L. fricii
Binomial name
Lophophora fricii
Haberm. 1975
Synonyms
  • Lophophora diffusa subsp. fricii (Haberm.) Halda 1997
  • Lophophora williamsii var. fricii (Haberm.) Grym 1997
  • Peyotl zacatensis var. fricii (Haberm.) Sotom. 2001

Lophophora fricii, also known as false peyote, is a species of Lophophora found in Mexico.[1][2][3]

Constituents and effects

In terms of total alkaloid content, Lophophora fricii contains 65.4% pellotine, 25.4% anhalonidine, and 1.0% mescaline.[4] For comparison, Lophophora williamsii (peyote) contains 30% mescaline, 17% pellotine, and 14% anhalonidine, whereas Lophophora diffusa (false peyote) contains 86% pellotine, 3.8% anhalonidine, and 1.2% mescaline.[4] In contrast to peyote, false peyotes like Lophophora fricii and Lophophora diffusa are said to not produce hallucinogenic effects.[2] Whereas mescaline is a psychedelic drug, pellotine and anhalonidine are known to produce sedative and hypnotic effects.[4][5]

See also

References

  1. ↑ "Plants of the World Online". Plants of the World Online. Retrieved 2026-01-25.
  2. 1 2 Ali, Ehsan; Azhar, Muhammad Farooq; Laila, Ume (23 January 2025). "False Peyote (Lophophora diffusa (Croizat) Bravo Cactaceae)". Comprehensive Guide to Hallucinogenic Plants. Boca Raton: CRC Press. p. 37–41. doi:10.1201/9781003460336-7. ISBN 978-1-003-46033-6. Retrieved 27 June 2026. When we refer to 'True peyote', we are typically talking about L. williamsii specifically. On the other hand, all other cacti species related to peyote are considered 'false peyote'. Lophophora diffusa and Lophophora fricii are commonly referred to as 'false peyote', but there are other species like Ariocarpus retusus that resemble L. williamsii in terms of appearance, alkaloid content, habitat, or genetic relationship (Chan et al., 2021). False peyotes thrive in identical environments and resemble peyote in appearance (Šnicer et al., 2009). In traditional situations, they have also been utilized as alternatives for peyote, albeit they often lack or have modest mescaline effects (Rätsch, 2005; Chaachouay et al., 2019).
  3. ↑ Niesel, Christian (2018). "A journey to the Mexican genus Lophophora". CactusWorld. 36 (1). British Cactus and Succulent Society: 5–14. ISSN 1751-1429. JSTOR 26533061. Archived from the original on 8 July 2026. Retrieved 28 June 2026.
  4. 1 2 3 Chan CB, Poulie CB, Wismann SS, Soelberg J, Kristensen JL (August 2021). "The Alkaloids from Lophophora diffusa and Other "False Peyotes"". J Nat Prod. 84 (8): 2398–2407. doi:10.1021/acs.jnatprod.1c00381. PMID 34264089.
  5. ↑ Poulie CB, Chan CB, Parka A, Lettorp M, Vos J, Raaschou A, Pottie E, Bundgaard MS, Sørensen LM, Cecchi CR, Märcher-Rørsted E, Bach A, Herth MM, Decker A, Jensen AA, Elfving B, Kretschmann AC, Stove CP, Kohlmeier KA, Cornett C, Janfelt C, Kornum BR, Kristensen JL (October 2023). "In Vitro and In Vivo Evaluation of Pellotine: A Hypnotic Lophophora Alkaloid". ACS Pharmacol Transl Sci. 6 (10): 1492–1507. doi:10.1021/acsptsci.3c00142. PMC 10580395. PMID 37854625.
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