Lysocardiolipin acyltransferase 1

LCLAT1
Identifiers
Aliases	LCLAT1, 1AGPAT8, AGPAT8, ALCAT1, HSRG1849, LYCAT, UNQ1849, lysocardiolipin acyltransferase 1
External IDs	OMIM: 614241; MGI: 2684937; GeneCards: LCLAT1
Enzyme activity
Gene location (Human)
Chr.	Chromosome 2 (human)
End	30,644,225 bp
Gene location (Mouse)
Chr.	Chromosome 17 (mouse)
End	73,550,363 bp
RNA expression pattern
	Top expressed in
	myocardium of left ventricle; ; pancreatic epithelial cell; ; mucosa of ileum; ; pancreatic ductal cell; ; endothelial cell; ; testicle; ; jejunal mucosa; ; saphenous vein; ; right ventricle; ; bronchial epithelial cell;
	Top expressed in
	epithelium of small intestine; ; right ventricle; ; Ileal epithelium; ; saccule; ; myocardium of ventricle; ; cardiac muscle tissue of left ventricle; ; interventricular septum; ; otic placode; ; calvaria; ; otic vesicle;
	More reference expression data
	n/a
Gene ontology
Molecular function	transferase activity; acyltransferase activity; protein binding; O-acyltransferase activity; 1-acylglycerol-3-phosphate O-acyltransferase activity;
Cellular component	integral component of membrane; endoplasmic reticulum membrane; membrane; endoplasmic reticulum; cytosol;
Biological process	phosphatidic acid biosynthetic process; multicellular organism development; CDP-diacylglycerol biosynthetic process; metabolism; cardiolipin acyl-chain remodeling; lipid metabolism; phospholipid biosynthetic process; phospholipid metabolic process; phosphatidylinositol acyl-chain remodeling;
	Sources:Amigo / QuickGO
Orthologs
Databases	NCBI: entry; OMA: entry
	253558
	225010
	ENSG00000172954
	ENSMUSG00000054469
	Q6UWP7
	Q3UN02
	NM_001002257; NM_001304445; NM_001304446; NM_182551
	NM_001081071; NM_001177967; NM_001177968
	NP_001002257; NP_001291374; NP_001291375; NP_872357
	NP_001074540; NP_001171438; NP_001171439
	Wikidata
View/Edit Human	View/Edit Mouse

Lysocardiolipin acyltransferase 1 is a protein that in humans is encoded by the LCLAT1 gene.^[5]

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000172954 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000054469 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Entrez Gene: Lysocardiolipin acyltransferase 1". Retrieved 2018-01-18.

References

Further reading