L-mimosine synthase
| L-mimosine synthase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.5.1.52 | ||||||||
| CAS no. | 93229-75-5 | ||||||||
| Databases | |||||||||
| BRENDA | enzyme data | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | enzyme entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| Rhea | reactions | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
L-mimosine synthase (EC 2.5.1.52) is an enzyme that catalyzes the chemical reaction
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The two substrates of this enzyme characterised from Leucaena leucocephala are O-acetylserine and 3,4-dihydroxypyridine (shown in its pyridin-4(1H)-one tautomer (1)). Its products are mimosine and acetic acid (CH3CO2H).[1] The enzyme has a similar function to cysteine synthase and beta-pyrazolylalanine synthase from watermelon.[2]
This enzyme is a transferase, specifically those transferring aryl or alkyl groups other than methyl groups. The systematic name of this enzyme class is O3-acetyl-L-serine:3,4-dihydroxypyridine 1-(2-amino-2-carboxyethyl)transferase. Other names in common use include O3-acetyl-L-serine acetate-lyase (adding 3,4-dihydroxypyridin-1-yl), 3-O-acetyl-L-serine:3,4-dihydroxypyridine, and 1-(2-amino-2-carboxyethyl)transferase.[3]
References
- ↑ Murakoshi, Isamu; Ikegami, Fumio; Hinuma, Yasuko; Hanma, Yukari (1984). "Purification and characterization of L-mimosine synthase from Leucaena leucocephala". Phytochemistry. 23 (9): 1905–1908. doi:10.1016/S0031-9422(00)84938-9.
- ↑ Noji, M.; Murakoshi, I.; Saito, K. (1993). "Evidence for Identity of β-Pyrazolealanine Synthase with Cysteine Synthase in Watermelon: Formation of β-Pyrazolealanine by Cloned Cysteine Synthase in Vitro and in Vivo". Biochemical and Biophysical Research Communications. 197 (3): 1111–1117. doi:10.1006/bbrc.1993.2592. PMID 8280125.
- ↑ Enzyme 2.5.1.52 at KEGG Pathway Database.