Kruppel like factor 16

KLF16
Identifiers
Aliases	KLF16, BTEB4, DRRF, NSLP2, Kruppel-like factor 16, Kruppel like factor 16
External IDs	OMIM: 606139; MGI: 2153049; GeneCards: KLF16
Gene location (Human) Chr. Chromosome 19 (human) Band 19p13.3 Start 1,852,399 bp End 1,863,579 bp
Gene location (Mouse) Chr. Chromosome 10 (mouse) Band 10|10 C1 Start 80,402,958 bp End 80,413,155 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in nucleus accumbens putamen caudate nucleus granulocyte cingulate gyrus anterior cingulate cortex amygdala monocyte right frontal lobe prefrontal cortex Top expressed in zygote superior frontal gyrus visual cortex dentate gyrus of hippocampal formation granule cell cumulus cell secondary oocyte primary visual cortex epiblast primary oocyte female urethra More reference expression data BioGPS n/a
Gene ontology Molecular function DNA-binding transcription factor activity RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA binding DNA-binding transcription repressor activity, RNA polymerase II-specific metal ion binding nucleic acid binding DNA-binding transcription factor activity, RNA polymerase II-specific Cellular component nucleus Biological process regulation of transcription by RNA polymerase II dopamine receptor signaling pathway regulation of transcription, DNA-templated negative regulation of transcription by RNA polymerase II transcription, DNA-templated Sources:Amigo / QuickGO
Orthologs Databases NCBI: entry; OMA: entry Species Human Mouse Entrez 83855 118445 Ensembl ENSG00000129911 ENSMUSG00000035397 UniProt Q9BXK1 P58334 RefSeq (mRNA) NM_031918 NM_078477 RefSeq (protein) NP_114124 NP_510962 Location (UCSC) Chr 19: 1.85 – 1.86 Mb Chr 10: 80.4 – 80.41 Mb PubMed search
Wikidata
View/Edit Human View/Edit Mouse

Kruppel like factor 16 is a protein that in humans is encoded by the KLF16 gene.

Further reading

• Kaczynski JA, Conley AA, Fernandez Zapico M, Delgado SM, Zhang JS, Urrutia R (September 2002). "Functional analysis of basic transcription element (BTE)-binding protein (BTEB) 3 and BTEB4, a novel Sp1-like protein, reveals a subfamily of transcriptional repressors for the BTE site of the cytochrome P4501A1 gene promoter". Biochem. J. 366 (Pt 3): 873–82. doi:10.1042/BJ20020388. PMC 1222816. PMID 12036432.
• Kanazawa A, Kawamura Y, Sekine A, Iida A, Tsunoda T, Kashiwagi A, Tanaka Y, Babazono T, Matsuda M, Kawai K, Iiizumi T, Fujioka T, Imanishi M, Kaku K, Iwamoto Y, Kawamori R, Kikkawa R, Nakamura Y, Maeda S (July 2005). "Single nucleotide polymorphisms in the gene encoding Krüppel-like factor 7 are associated with type 2 diabetes". Diabetologia. 48 (7): 1315–22. doi:10.1007/s00125-005-1797-0. PMID 15937668.
• Gutiérrez-Aguilar R, Benmezroua Y, Vaillant E, Balkau B, Marre M, Charpentier G, Sladek R, Froguel P, Neve B (August 2007). "Analysis of KLF transcription factor family gene variants in type 2 diabetes". BMC Med. Genet. 8 53. doi:10.1186/1471-2350-8-53. PMC 1994949. PMID 17688680.