Isaac Johnson

Isaac Johnson may refer to:

• Isaac Johnson (politician) (1803–1853), governor of Louisiana
• Isaac Johnson (colonist) (1601–1630), English clergyman and one of the Puritan founders of Massachusetts
• Isaac Johnson (cricketer) (1808–1874), English cricketer
• Isaac Johnson (racing driver) (born 2000), American racing driver
• Isaac Charles Johnson (1811–1911), British cement manufacturer