Inositol 4-methyltransferase
| Inositol 4-methyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.1.1.129 | ||||||||
| Databases | |||||||||
| BRENDA | enzyme data | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | enzyme entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| Rhea | reactions | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
Inositol 4-methyltransferase (EC 2.1.1.129) is an enzyme that catalyzes the chemical reaction
This is a methylation reaction in which inositol (myo-inositol) is converted to ononitol. The methyl group comes from the cofactor, S-adenosyl methionine (SAM), which becomes S-adenosyl-L-homocysteine (SAH). The enzyme has been characterised from Mesembryanthemum crystallinum and Vigna umbellata.[1][2]
This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:1D-myo-inositol 4-methyltransferase. Other names in common use include myo-inositol 4-O-methyltransferase, S-adenosyl-L-methionine:myo-inositol 4-O-methyltransferase, and myo-inositol 6-O-methyltransferase.[3]
References
- ↑ Vernon DM, Bohnert HJ (1992). "A novel methyl transferase induced by osmotic stress in the facultative halophyte Mesembryanthemum crystallinum". EMBO J. 11 (6): 2077–85. doi:10.1002/j.1460-2075.1992.tb05266.x. PMC 556674. PMID 1600940.
- ↑ Wanek W; Richter A (1995). "Purification and characterization of myo-inositol 6-O-methyltransferase from Vigna umbellata Ohwi et Ohashi". Planta. 197 (3): 427–434. Bibcode:1995Plant.197..427W. doi:10.1007/bf00196663.
- ↑ Enzyme 2.1.1.129 at KEGG Pathway Database.