INO80 complex subunit B

INO80B
Identifiers
AliasesINO80B, HMGA1L4, HMGIYL4, IES2, PAP-1BP, PAPA-1, ZNHIT4, hIes2, PAPA1, INO80 complex subunit B
External IDsOMIM: 616456; MGI: 1917270; GeneCards: INO80B
Orthologs
DatabasesNCBI: entry; OMA: entry
SpeciesHumanMouse
Entrez

83444

70020

Ensembl

ENSG00000115274

ENSMUSG00000030034

UniProt

Q9C086

Q99PT3

RefSeq (mRNA)

NM_031288

NM_023547

RefSeq (protein)

NP_112578

NP_076036

Location (UCSC)Chr 2: 74.46 – 74.46 MbChr 6: 83.1 – 83.1 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

INO80 complex subunit B is a protein that in humans is encoded by the INO80B gene.[5]

INO80 stabilizes replication forks and counteracts mislocalization of H2A.Z

Function

This gene encodes a subunit of an ATP-dependent chromatin remodeling complex, INO80, which plays a role in DNA and nucleosome-activated ATPase activity and ATP-dependent nucleosome sliding. Readthrough transcription of this gene into the neighboring downstream gene, which encodes WW domain-binding protein 1, generates a non-coding transcript.

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000115274 – Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000030034 – Ensembl, May 2017
  3. ↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ↑ "Entrez Gene: INO80 complex subunit B". Retrieved 2016-12-13.

Further reading


This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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