Glucose-1-phosphatase
| glucose-1-phosphatase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 3.1.3.10 | ||||||||
| CAS no. | 9001-38-1 | ||||||||
| Databases | |||||||||
| BRENDA | enzyme data | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | enzyme entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| Rhea | reactions | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
The enzyme glucose-1-phosphatase (EC 3.1.3.10) catalyzes the reaction
The enzyme characterised from silkworm and pea seeds hydrolyses glucose 1-phosphate to D-glucose and orthophosphate.[1][2][3] In some organisms such as the bacterium Pantoea species strain 3.5.1, glucose-1-phosphatase behaves as a phytase, allowing uptake of phosphate from soil.[4]
This enzyme is a hydrolase, specifically one acting on phosphoric monoester bonds. The systematic name is α-D-glucose-1-phosphate phosphohydrolase.[5]
Structural studies
As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code PDB: 1NT4.
References
- ↑ Faulkner P (August 1955). "A hexose-1-phosphatase in silkworm blood". The Biochemical Journal. 60 (4): 590–6. doi:10.1042/bj0600590. PMC 1216157. PMID 13249953.
- ↑ Turner DH, Turner JF (March 1960). "The hydrolysis of glucose monophosphates by a phosphatase preparation from pea seeds". The Biochemical Journal. 74 (3): 486–91. doi:10.1042/bj0740486. PMC 1204246. PMID 13839934.
- ↑ Schomburg, Dietmar; Salzmann, Margit (1991). "Glucose-1-phosphatase". Enzyme Handbook 3. pp. 335–337. doi:10.1007/978-3-642-76463-9_71. ISBN 978-3-642-48962-4.
- ↑ Suleimanova, Aliya D.; Beinhauer, Astrid; Valeeva, Liia R.; Chastukhina, Inna B.; Balaban, Nelly P.; Shakirov, Eugene V.; Greiner, Ralf; Sharipova, Margarita R. (2015). "Novel Glucose-1-Phosphatase with High Phytase Activity and Unusual Metal Ion Activation from Soil Bacterium Pantoea sp. Strain 3.5.1". Applied and Environmental Microbiology. 81 (19): 6790–6799. doi:10.1128/aem.01384-15. PMC 4561695. PMID 26209662.
- ↑ Enzyme 3.1.3.10 at KEGG Pathway Database.
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