Fe3+-transporting ATPase

ferric-transporting ATPase
Identifiers
EC no.	7.2.2.7
Databases
BRENDA	enzyme data
ExPASy	NiceZyme view
KEGG	enzyme entry
MetaCyc	metabolic pathway
Rhea	reactions
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / QuickGO
Search PMC articles PubMed articles NCBI proteins

In enzymology, a Fe3+-transporting ATPase (EC 7.2.2.7) is an enzyme that catalyzes the chemical reaction

ATP + H₂O + Fe₃+out $\rightleftharpoons$ ADP + phosphate + Fe₃+in

The 3 substrates of this enzyme are ATP, H₂O, and Fe3+, whereas its 3 products are ADP, phosphate, and Fe3+.

This enzyme belongs to the family of hydrolases, specifically those acting on acid anhydrides to catalyse transmembrane movement of substances. The systematic name of this enzyme class is ATP phosphohydrolase (ferric-ion-transporting). This enzyme participates in abc transporters - general.

References

• Angerer A, Klupp B, Braun V (1992). "Iron transport systems of Serratia marcescens". J. Bacteriol. 174 (4): 1378–87. doi:10.1128/jb.174.4.1378-1387.1992. PMC 206435. PMID 1531225.
• Kuan G, Dassa E, Saurin W, Hofnung M, Saier MH Jr (1995). "Phylogenetic analyses of the ATP-binding constituents of bacterial extracytoplasmic receptor-dependent ABC-type nutrient uptake permeases". Res. Microbiol. 146 (4): 271–8. doi:10.1016/0923-2508(96)81050-3. PMID 7569321.
• Saier MH Jr (1998). "Molecular phylogeny as a basis for the classification of transport proteins from bacteria, archaea and eukarya". Adv. Microb. Physiol. Advances in Microbial Physiology. 40: 81–136. doi:10.1016/S0065-2911(08)60130-7. ISBN 978-0-12-027740-7. PMID 9889977.{{cite journal}}: CS1 maint: periodical has ISBN (link)
• Khun HH, Kirby SD, Lee BC (1998). "A Neisseria meningitidis fbpABC mutant is incapable of using nonheme iron for growth". Infect. Immun. 66 (5): 2330–6. doi:10.1128/IAI.66.5.2330-2336.1998. PMC 108199. PMID 9573125.