Exoribonuclease H
| Exoribonuclease H | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 3.1.13.2 | ||||||||
| Databases | |||||||||
| BRENDA | enzyme data | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | enzyme entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| Rhea | reactions | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
Exoribonuclease H (EC 3.1.13.2) is an enzyme.[1] This enzyme catalyses the following chemical reaction
- 3'-end directed exonucleolytic cleavage of viral RNA-DNA hybrid
This is a secondary reaction to the RNA 5'-end directed cleavage 13-19 nucleotides from the RNA end performed by EC 3.1.26.13 (retroviral ribonuclease H).
References
- ↑ Schatz O, Mous J, Le Grice SF (April 1990). "HIV-1 RT-associated ribonuclease H displays both endonuclease and 3'----5' exonuclease activity". The EMBO Journal. 9 (4): 1171–6. doi:10.1002/j.1460-2075.1990.tb08224.x. PMC 551793. PMID 1691093.
External links
- Exoribonuclease+H at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
Category: