Cycloartenol 24-C-methyltransferase

Cycloartenol 24-C-methyltransferase
Identifiers
EC no.2.1.1.142
Databases
BRENDAenzyme data
ExPASyNiceZyme view
KEGGenzyme entry
MetaCycmetabolic pathway
Rheareactions
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
Search
PMCarticles
PubMedarticles
NCBIproteins

Cycloartenol 24-C-methyltransferase (EC 2.1.1.142) is an enzyme that catalyzes the chemical reaction

2D representation of the chemical structure of cycloartenol .
cycloartenol
+ SAM
 
 
 
 
Rightward reaction arrow
 
 
 
2D representation of the chemical structure of Q27256667.
cyclolaudenol
+ SAH
 

This is a methylation reaction in which the phytosterol, cycloartenol, is converted to cyclolaudenol. The methyl group comes from the cofactor, S-adenosyl methionine (SAM), which becomes S-adenosyl-L-homocysteine (SAH). The enzyme was characterised from the green alga Prototheca wickerhamii.[1]

This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:cycloartenol 24-C-methyltransferase. This enzyme is also called sterol C-methyltransferase.[2]

References

  1. ↑ Mangla AT, Nes WD (2000). "Sterol C-methyl transferase from Prototheca wickerhamii mechanism, sterol specificity and inhibition". Bioorg. Med. Chem. 8 (5): 925–36. doi:10.1016/S0968-0896(00)00040-7. PMID 10882005.
  2. ↑ Enzyme 2.1.1.142 at KEGG Pathway Database.


This page is issued from Wikipedia. The text is available under Creative Commons Attribution-Share Alike 4.0 unless otherwise noted. Additional terms may apply for the media files.