Craig Ritchie

Craig Ritchie
Born
Aberdeen, Scotland
Alma materUniversity of Aberdeen
University College London (UCL)
Known forEuropean Prevention of Alzheimer's Dementia (EPAD)
PREVENT Dementia Programme
Brain Health Scotland
Scientific career
FieldsPsychiatry, Neurodegeneration, Epidemiology, Brain Health
WorkplacesUniversity of St Andrews
Scottish Brain Sciences
University of Edinburgh (former)
Imperial College London (former)
WebsiteScottish Brain Sciences

Craig Ritchie is a Scottish professor of psychiatry specialising in the early diagnosis and treatment of Alzheimer's disease. He is the founder and chief executive officer of Scottish Brain Sciences and Professor of Brain Health and Neurodegenerative Disease at the University of St Andrews.[1][2]

Ritchie has argued for detecting Alzheimer's disease in midlife, decades before the onset of dementia symptoms, an approach he has termed "brain health".[3] He previously held the Chair in Psychiatry of Ageing at the University of Edinburgh and was the inaugural Director of Brain Health Scotland, a government-funded dementia prevention initiative.[4]

Early life and education

Ritchie was born in Aberdeen, Scotland.[5] He attended Aberdeen Grammar School before studying at the University of Aberdeen, graduating with a Bachelor of Medicine, Bachelor of Surgery (MBChB) in 1991.[1][5]

Early career

Between 1997 and 2000, Ritchie worked as a researcher in Melbourne, Australia, in a laboratory run by Professor Colin Masters at the University of Melbourne, focusing on drug discovery for Alzheimer's disease.[6][7] He returned to the United Kingdom in 2000 and completed an MSc in Epidemiology and, between 2002 and 2006, a PhD in Mental Health at University College London, funded by a Medical Research Council Health Services Research Fellowship.[1][4]

Clinical and academic career

In 2007, Ritchie was appointed Senior Lecturer in Old Age Psychiatry at Imperial College London, where he also held several NHS and research-network leadership roles between 2010 and 2014, including Research and Development Director at West London Mental Health Trust and Deputy Director of the London Northwest National Institute for Health and Care Research (NIHR) Clinical Research Network.[4][6][5]

In October 2014, Ritchie returned to Scotland to take up the Chair in Psychiatry of Ageing at the University of Edinburgh, where he established the Centre for Dementia Prevention in 2015.[8][4] He was elected Chair of the Scottish Dementia Research Consortium from 2017 to 2022 and Associate Director of the Edinburgh Wellcome Trust Clinical Research Facility from 2016 to 2022.[1] He is currently Professor of Brain Health and Neurodegenerative Disease at the University of St Andrews.[2]

Brain Health Scotland

In March 2020, Ritchie became the inaugural Director of Brain Health Scotland, a government-sponsored programme led by Alzheimer Scotland that works to reduce dementia risk across the life course.[4][9] In this role, he advocated for a distinct national brain health strategy focused on public health, risk reduction and early detection, alongside existing dementia care strategies.[10]

Scottish Brain Sciences

In 2022, Ritchie founded Scottish Brain Sciences, a company that runs clinical trials and research into diagnostics and therapeutics for neurodegenerative disease, opening its first clinical research centre in Edinburgh.[4] In May 2023, after 33 years working as a psychiatrist in NHS Scotland, he resigned, citing frustration with the infrastructure available to deliver new Alzheimer's treatments and stating that patients faced waits of up to 18 months for diagnosis.[11][12]

His resignation was raised in the Scottish Parliament during First Minister's Questions, where MSP Claire Baker asked for the Scottish Government's response; First Minister Humza Yousaf said the government shared Ritchie's ambition to improve dementia care and took his criticisms seriously.[13]

Ritchie then became full-time CEO of Scottish Brain Sciences, which operates a "triple helix" model connecting life-sciences companies, universities and the health sector.[4][14] In August 2023, BBC News reported on the company's partnership with Roche Diagnostics to develop a blood test for earlier detection of Alzheimer's disease.[15] In November 2025, Scotland's Deputy First Minister Kate Forbes attended the opening of a new Scottish Brain Sciences research centre at the ONE BioHub in Aberdeen.[16][17]

Research roles and projects

  • European Prevention of Alzheimer's Dementia (EPAD): From 2015 to 2020, Ritchie led the EPAD Consortium, a €64 million Innovative Medicines Initiative-funded project that built a longitudinal cohort of over 2,000 participants as a trial-readiness platform.[18]
  • PREVENT Dementia Programme: Ritchie is Chief Investigator of PREVENT, a multi-centre cohort study examining midlife (ages 40–59) risk factors for dementia.[19]

Media

Ritchie has appeared in national media discussing dementia prevention and NHS dementia care. He was interviewed by The Sunday Times about his NHS resignation in May 2023 and about dementia research in February 2024.[11][20] He was interviewed by Michael Mosley for the BBC Two programme Trust Me, I'm a Doctor in 2015, and featured in the BBC Scotland documentary Sally Magnusson: Alzheimer's, a Cure and Me in 2024.[21][8][22]

Selected publications

  • Ritchie, C.W., et al. (2016). "Development of interventions for the secondary prevention of Alzheimer's dementia: the European Prevention of Alzheimer's Dementia (EPAD) project." The Lancet Psychiatry.[18]
  • Ritchie, C.W., et al. (2024). "The PREVENT dementia programme: baseline demographic, lifestyle, imaging and cognitive data from a midlife cohort study investigating risk factors for dementia." Brain Communications.[19]
  • Laurell, A.A.S., et al. (2025). "Hypothalamic volume, sleep, and APOE genotype in cognitively healthy adults." Alzheimer's & Dementia.[23]
  • Ritchie, C.W., Trepel, D., et al. (2025). "The impact of mild cognitive impairment on healthcare utilization and costs: A UK Biobank study." Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring.[24]

References

  1. 1 2 3 4 "Leadership Team: Prof Craig Ritchie". Scottish Brain Sciences. 15 May 2023.
  2. 1 2 "Professor Craig Ritchie". University of St Andrews Research Portal.
  3. ↑ "Inside the Impact Board: Why Dr. Craig Ritchie Is Optimistic About StartUp Health's Alzheimer's Moonshot Community". StartUp Health. 2024-07-30.
  4. 1 2 3 4 5 6 7 "Craig Ritchie - Expert Advisory Panel". Alzheimer Europe.
  5. 1 2 3 "Profile – Professor Craig Ritchie". Dementia Researcher. 2021-10-16.
  6. 1 2 "Prof Craig Ritchie Profile". Neurology Academy.
  7. ↑ "Why Dr. Craig Ritchie Brings Optimism to StartUp Health's Alzheimer's Moonshot Impact Board". StartUp Health NOW Podcast. 2024-05-30.
  8. 1 2 "Paving the Way for Dementia Prevention". University of Edinburgh. 2024-09-09.
  9. ↑ "Your Brain is Amazing. Let's Keep it That Way". Brain Health Scotland.
  10. ↑ "A Strategy for Brain Health". Scottish Brain Sciences. 6 June 2023.
  11. 1 2 Puttick, Helen (2023-05-20). "Dementia expert quits 'failing' NHS Scotland". The Sunday Times.
  12. ↑ Wilson, Caroline (2023-05-20). "Dementia expert Professor Craig Ritchie quits NHS job". The Herald.
  13. ↑ "Meeting of the Parliament: 25 May 2023". Scottish Parliament TV. 2023-05-25.
  14. ↑ Ritchie, Craig (2024-05-29). Can We Prevent and Cure Alzheimer's? (Video). Scottish Brain Sciences.
  15. ↑ "Edinburgh firm developing early Alzheimer's test". BBC News. 2023-08-14.
  16. ↑ "Deputy First Minister announces Scottish Brain Sciences as anchor tenant in ONE BioHub Aberdeen". Scottish Brain Sciences. 17 July 2024.
  17. ↑ Pinching, John (2025-11-17). "Scottish Brain Sciences opens new Alzheimer's research centre in Aberdeen". PharmaTimes.
  18. 1 2 Ritchie CW, Molinuevo JL, Truyen L, Satlin A, Van der Geyten S, Lovestone S (2016). "Development of interventions for the secondary prevention of Alzheimer's dementia: the European Prevention of Alzheimer's Dementia (EPAD) project". The Lancet Psychiatry. 3 (2): 179–186. doi:10.1016/S2215-0366(15)00454-X. PMID 26683239.
  19. 1 2 Ritchie CW, Bridgeman K, Gregory S, et al. (2024). "The PREVENT dementia programme: baseline demographic, lifestyle, imaging and cognitive data from a midlife cohort study investigating risk factors for dementia". Brain Communications. 6 (3) fcae189. doi:10.1093/braincomms/fcae189. PMC 11166176. PMID 38863576.
  20. ↑ Andrews, Kieran (2024-02-26). "Cure for Alzheimer's 'can be found within ten years'". The Sunday Times.
  21. ↑ Mosley, Michael; Ritchie, Craig (2015-07-15). How can we all avoid dementia? (Television production). BBC Two.
  22. ↑ Magnusson, Sally (2024-10-10). "Will I be diagnosed with Alzheimer's like my mother?". BBC News.
  23. ↑ Laurell, Axel A. S.; Mak, Elijah; Dounavi, Maria-Eleni; Underwood, Benjamin R.; Dauvilliers, Yves; et al. (2025-05-12). "Hypothalamic volume, sleep, and APOE genotype in cognitively healthy adults". Alzheimer's & Dementia. 21 (5) e70244. doi:10.1002/alz.70244. PMC 12069023. PMID 40356022.
  24. ↑ Ritchie C, Trepel D, Edwards S, Hahn-Pedersen JH, Chan MS, Bray BD, Clark A, Wichmann CA, Evans M (2025). "The impact of mild cognitive impairment on healthcare utilization and costs: A UK Biobank study". Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring. 17 (2) e70065. doi:10.1002/dad2.70065. PMC 12159762. PMID 40510591.
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