Claude Griscelli

Claude Griscelli
Member of the Conseil d'État
In office
11 December 2000 – 7 May 2026
President of Inserm
In office
24 July 1996 – 15 February 2001
Preceded byPhilippe Lazar
Succeeded byChristian Bréchot
Personal details
Born(1936-03-02)2 March 1936
Rabat, French protectorate in Morocco
Died7 May 2026(2026-05-07) (aged 90)
Morocco
EducationLycée Descartes
University of Paris Faculty of Medicine
OccupationDoctor
Immunologist

Claude Griscelli (French: [klˈod ɡʁisɛlˈi]; 2 March 1936 – 7 May 2026) was a French doctor and immunologist.[1]

Life and career

Born in Rabat on 2 March 1936, Griscelli grew up in a Corsican family and attended the Lycée Gouraud and the University of Paris Faculty of Medicine.[2] He began researching for Inserm at the Hôpital Saint-Louis in Paris before a stint in the United States with the National Institutes of Health.[3][4] He returned to France in 1968 and became chief clinician of pediatrics at Necker–Enfants Malades Hospital.[5][6] There, he established a research laboratory to continue work he had begun in the United States.[7] From 1978 to 1992, he directed Inserm's Research Unit in Pediatric Immunology and Rheumatology.[8] He served as president of Inserm from 1996 to 2001, where he notably created the institute's ethics committee.[9]

In 2007, Griscelli founded the Institut des maladies génétiques Imagine, which studied genetic diseases at Necker Hospital.[10] The institute became part of the French government initiative Investissements d'avenir, or future investments.[11] Under his leadership, the institute created a team of over 450 doctors, researchers, and technicians.[12] He oversaw an advisory board composed of several highly-distinguished scientists.[13] In 2011, he was implicated in the Mediator affair, in which a diabetes and diet pill sold by Laboratoires Servier under the name Mediator, was found to have caused fatal heart valve damage, causing between 500 and 2000 deaths, and was thereafter covered up.[14] He was accused of attempting to downplay his laboratory's liability in the scandal, but was ultimately acquitted on 29 March 2021.[15] However, he was removed from the Conseil national de l'Ordre des médecins on 29 December 2023.[16] His removal was in connection to his numerous attempts to downplay his contractual, paid relationship with Servier since 2001.[17] In spite of this, he was still named a Grand Officer of the Legion of Honour in 2021.[18]

Griscelli died in Morocco on 7 May 2026, at the age of 90.[19]

References

  1. ↑ "Décès du Pr Claude Griscelli, sommité du monde médical". Corse-Matin (in French). 7 May 2026. Retrieved 8 May 2026.
  2. ↑ "Maxime Seligmann". Inserm (in French). Archived from the original on 1 October 2022.
  3. ↑ "Baruj Benacerraf". Le Monde (in French). 27 August 2011. Retrieved 8 May 2026.
  4. ↑ "Claude Griscelli". Inserm (in French). Archived from the original on 1 October 2022.
  5. ↑ Weil-Halpern, Françoise (1994). Oubliés des fées (in French). Calmann-Lévy. ISBN 978-2-7021-5093-1. Retrieved 8 May 2026.
  6. ↑ "Hôpital Necker-Enfants malades". Inserm (in French). Archived from the original on 20 November 2022.
  7. ↑ "Delphine Guy-Grand". Pasteur Institute (in French).
  8. ↑ "De l'INH à l'Inserm". Inserm (in French). Archived from the original on 27 July 2021.
  9. ↑ "Le Comité ERMES : Une transformation à la hauteur des enjeux de l'Ethique". Gazette Labo (in French). Archived from the original on 14 February 2018.
  10. ↑ "Membres fondateurs". Institut des maladies génétiques Imagine (in French). Archived from the original on 20 July 2014.
  11. ↑ "Le Conseil d'administration". Institut des maladies génétiques Imagine (in French). Archived from the original on 20 July 2014.
  12. ↑ "Nos équipes". Institut des maladies génétiques Imagine (in French). Archived from the original on 22 June 2014.
  13. ↑ "Le conseil scientifique international". Institut des maladies génétiques Imagine (in French). Archived from the original on 22 January 2015.
  14. ↑ Jouan, Anne (13 September 2011). "Mediator : comment Servier a corrigé le rapport du Sénat". Le Figaro (in French). Retrieved 8 May 2026.
  15. ↑ Seckel, Henri (30 March 2021). "Procès du Mediator : le mensonge de Servier reconnu, les parties civiles partagées sur le jugement". Le Monde (in French). Retrieved 8 May 2026.
  16. ↑ Tranthimy, Loan (11 January 2024). "Mediator : le Pr Claude Griscelli radié par l'Ordre des médecins". Le Quotidien du médecin (in French). Retrieved 8 May 2026.
  17. ↑ "Mediator : Soupçonné d'avoir influencé une sénatrice, le Dr Claude Griscelli radié de l'ordre des médecins". 20 minutes (in French). 10 January 2024. Retrieved 8 May 2026.
  18. ↑ "Décret du 31 décembre 2021 portant élévation dans l'ordre national de la Légion d'honneur". Journal officiel de la République française (in French). 1 January 2022. Retrieved 8 May 2026.
  19. ↑ "Death of Professor Claude Griscelli, founder of the Institut Imagine". Institut des maladies génétiques Imagine (in French). 7 May 2026. Retrieved 8 May 2026.