Chlorogenate hydrolase
| chlorogenate hydrolase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 3.1.1.42 | ||||||||
| CAS no. | 74082-59-0 | ||||||||
| Databases | |||||||||
| BRENDA | enzyme data | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | enzyme entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| Rhea | reactions | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
Chlorogenate hydrolase (EC 3.1.1.42) is an enzyme that catalyzes the reaction
The enzyme characterised from Aspergillus niger hydrolyses chlorogenic acid to quinic acid and caffeic acid.[1][2] The enzyme has been used for the large-scale production of its products.[3] Since the reaction is reversible, it has also been used to make alternative esters of caffeic acid.[4]
This enzyme is a hydrolase, specifically one acting on carboxylic ester bonds. The systematic name is chlorogenate hydrolase. Other names in use include chlorogenase, and chlorogenic acid esterase.[5]
References
- ↑ Schobel B, Pollmann W (1980). "Isolation and characterization of a chlorogenic acid esterase from Aspergillus niger". Z. Naturforsch. C. 35 (3–4): 209–12. doi:10.1515/znc-1980-3-407. PMID 7385941.
- ↑ Schobel B, Pollmann W (1980). "Weitere Charakterisierung einer Chlorogensäure - Hydrolase aus Aspergillus niger [Further characterization of a chlorogenic acid hydrolase from Aspergillus niger (author's transl)]". Z. Naturforsch. C. 35 (9–10): 699–701. doi:10.1515/znc-1980-9-1006. PMID 7445677.
- ↑ Butiuk, Ana P.; Maidana, Silvana A.; Martos, María A.; Akakabe, Yoshihiko; Adachi, Osao; Hours, Roque A. (2018). "Characterization and application of fungal chlorogenate hydrolase to enzymatic breaking down of chlorogenate from yerba mate". Biocatalysis and Agricultural Biotechnology. 14: 395–401. doi:10.1016/j.bcab.2018.04.005. hdl:11336/91820.
- ↑ Kurata, Atsushi; Takemoto, Shintaro; Fujita, Tokio; Iwai, Kazuya; Furusawa, Mina; Kishimoto, Noriaki (2011). "Synthesis of 3-cyclohexylpropyl caffeate from 5-caffeoylquinic acid with consecutive enzymatic conversions in ionic liquid". Journal of Molecular Catalysis B: Enzymatic. 69 (3–4): 161–167. doi:10.1016/j.molcatb.2011.01.012.
- ↑ Enzyme 3.1.1.42 at KEGG Pathway Database.
Categories: