ODAD3

ODAD3
Identifiers
Aliases	ODAD3, CILD30, coiled-coil domain containing 151, ODA10, CCDC151, outer dynein arm docking complex subunit 3
External IDs	OMIM: 615956; MGI: 1924859; GeneCards: ODAD3
Gene location (Human)
Chr.	Chromosome 19 (human)
End	11,435,782 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	21,913,930 bp
RNA expression pattern
	Top expressed in
	bronchial epithelial cell; ; right uterine tube; ; gonad; ; nasal epithelium; ; mucosa of paranasal sinus; ; olfactory zone of nasal mucosa; ; testicle; ; left testis; ; right testis; ; pituitary gland;
	Top expressed in
	seminiferous tubule; ; otolith organ; ; utricle; ; spermatocyte; ; morula; ; spermatid; ; olfactory epithelium; ; Epithelium of choroid plexus; ; embryo; ; embryo;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein binding;
Cellular component	cytoplasm; ciliary basal body; centriole; axoneme; cell projection; cilium; cytoskeleton;
Biological process	regulation of cilium assembly; determination of left/right symmetry; outer dynein arm assembly; cell projection organization; axonemal dynein complex assembly; cilium movement;
	Sources:Amigo / QuickGO
Orthologs
Databases	NCBI: entry; OMA: entry
	115948
	77609
	ENSG00000198003
	ENSMUSG00000039632
	A5D8V7
	Q8BSN3
	NM_145045; NM_001302453; NM_001302454
	NM_001163787; NM_029939
	NP_001289382; NP_001289383; NP_659482
	NP_001157259; NP_084215
	Wikidata
View/Edit Human	View/Edit Mouse

Outer dynein arm-docking complex subunit 3 is a protein that in humans is encoded by the ODAD3 gene (previously CCDC151).^[5] As its name suggests, ODAD3 is part of a protein complex called the "dynein arm-docking complex" (ODA-DC), which is involved in outer dynein arm assembly.^[6]

Clinical significance

Mutations in the gene ODAD3 are associated with Primary ciliary dyskinesia.^[7]

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000198003 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000039632 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Entrez Gene: Coiled-coil domain containing 151".
↑ "Outer dynein arm-docking complex subunit 3". uniprot.org. UniProt consortium. Retrieved 2026-08-14.
↑ Alsaadi MM, Erzurumluoglu AM, Rodriguez S, Guthrie PA, Gaunt TR, Omar HZ, Mubarak M, Alharbi KK, Al-Rikabi AC, Day IN (December 2014). "Nonsense mutation in coiled-coil domain containing 151 gene (CCDC151) causes primary ciliary dyskinesia". Human Mutation. 35 (12): 1446–8. doi:10.1002/humu.22698. PMC 4489323. PMID 25224326.

External links

Human CCDC151 genome location and CCDC151 gene details page in the UCSC Genome Browser.

[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000198003 – Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000039632 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: Coiled-coil domain containing 151".

[6] "Outer dynein arm-docking complex subunit 3". uniprot.org. UniProt consortium. Retrieved 2026-08-14.

[7] Alsaadi MM, Erzurumluoglu AM, Rodriguez S, Guthrie PA, Gaunt TR, Omar HZ, Mubarak M, Alharbi KK, Al-Rikabi AC, Day IN (December 2014). "Nonsense mutation in coiled-coil domain containing 151 gene (CCDC151) causes primary ciliary dyskinesia". Human Mutation. 35 (12): 1446–8. doi:10.1002/humu.22698. PMC 4489323. PMID 25224326.

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Clinical significance

References

Further reading

External links