Bing Liu (scientist)

Bing Liu (Chinese: 刘冰; 20 October 1982 – 2 May 2020) was a Chinese computational biologist[1] living and researching in the United States.[2] He was a Research Assistant Professor of Computational & Systems Biology Department at the University of Pittsburgh School of Medicine.[2] He was 37 years old at the time of his death, in which he was shot dead in his home. Due to Liu's research into coronavirus during the COVID-19 pandemic at the time of his death, the case received American and Chinese media coverage.[2]

Career

Liu graduated with a master's degree and Ph.D. in computer science from the National University of Singapore. He was a postdoctoral researcher at Carnegie Mellon University.[3][4] Both he and his wife retained Chinese citizenship.[5][6]

Death

Liu was found dead at his home in Ross Township, a suburb north of Pittsburgh, on 2 May 2020.[2][7] His work on coronaviruses led to speculation that his murder was related to his work, but Pittsburgh Police said that he was shot as a result of a murder-suicide.[2] The gunman was 46-year-old Hao Gu (Chinese: 顾浩), a software engineer from Moon Township, employed at Eaton Corporation.[2][8] The police said that the murder was the result of a dispute over an intimate partner and that after murdering Liu, the gunman had gone back to his car and shot himself.[2]

Works

Books

  • B Liu. Computational Modeling of Biological Pathways: Probabilistic Approximation and Analysis Techniques. Lambert Academic Publishing, ISBN 3847372114, Jan 2012. (176 pages)

Most recent articles

  • W Sun, V Tyurin, G Mao, I Shrivastava, B Liu, Y Zhai, S Korolev, A Abramov, P Angelova, I Miller, O Beharier, H Dar, O Kapralov, T Hastings, J Greenamyre, C Chu, I Bahar, Y Sadovsky, H Bayır, Y Tyurina, R He, V Kagan "iPLA2G6 Protects Cells against Ferroptosis by Hydrolyzing the Lipid Signal of Death, 15-HpETE-PE: Relevance to Parkinson Disease Pathogenesis, "Nature Neuroscience, under review (2020).
  • B Liu. "A Model Checking-based Analysis Framework for Systems Biology Models", The 57th ACM/IEEE Design Automation Conference (DAC), San Francisco, US (2020). IEEE, pp. 1–6
  • Q Shi, F Pei, G Silverman, S Pak, D Perlmutter, B Liu, I Bahar." Mechanisms of Action of Autophagy Modulators Dissected by Quantitative Systems Pharmacology Analysis," International Journal of Molecular Sciences, 21(8). 2855 (2020). doi: 10.3390/ijms21082855
  • S Thermozier, W Hou, X Zhang, D Shields, R Fisher, H Bayir, V Kagam, J Yu, B Liu, I Bahar, M W Epperly, P Wipf, H Wang, and J S Greenberger. "Anti-Ferroptosis Drug Enhances Total Body Irradiation Mitigation by Drugs that Block Apoptosis and Necroptosis," Radiation Research, [Epub ahead of print] (2020). doi: 10.1667/RR15486.1
  • O Kapralov, Q Yang, H Dar, Y Tyurina, T Anthonymuthu, R Kim, C St. Croix, K Mikulska-Ruminska, B Liu, I Shrivastava, V Tyurin, H-C Ting, Y Wu, Y Gao, R Domingues, D Stoyanovsky, R Mallampalli, I Bahar, D Gabrilovich, H Bayir, and V Kagan "Redox Lipid Reprogramming Commands Susceptibility of Macrophages and Microglia to Ferroptotic Death," Nature Chemical Biology, 16:2780-290 (2020). doi: 10.1038/s41589-019-0462-8
  • S Thermozier, X Zhang, W Hou, R Fisher, M W Epperly, B Liu, I Bahar, S Markovina, C Luke, G Silverman, and J S Greenberger. "Radioresistance of Serpinb3a-/- Mice and Derived Hematopoietic and Marrow Stromal Cell Lines," Radiation Research, 192(3):267-281 (2019). doi: 10.1667/RR15379.1.
  • F Pei, H Li, B Liu, I Bahar. "Quantitative Systems Pharmacological Analysis of Drugs of Abuse Reveals the Pleiotropy of Their Targets and the Effector Role of mTORC1", Frontiers in Pharmacology, 10:191 (2019). doi: 10.3389/fphar.2019.00191

Most highly cited articles

  • V E Kagan, G Mao, F Qu, J P F Angeli, S Doll, C S Croix, H Dar, B Liu, V A Tyurin, V B Ritov, O A Kapralov, A A Amoscato, J Jiang, T Anthonymuthu, D Mohammadyani, Q Yang, J Klein-Seetharaman, S Watkins, I Bahar, J Greenberger, R Mallampalli, B R Stockwell, Y Y Tyurina, M Conrad, H Bayir. Oxidized Arachidonic and Adrenic PEs Navigate Cells to Ferroptosis, Nature Chemical Biology, 13:81-90 (2017). doi:10.1038/nchembio.2238. Cited 320 times according to Google Scholar [9]
  • B Liu, J Zhang, P Y Tan, D Hsu, A M Blom, B Leong, S Sethi, B Ho, J L Ding, P S Thiagarajan. A Computational and Experimental Study of the Regulatory Mechanisms of the Complement System. PLoS Computational Biology, 7(1):e1001059 (2011).
  • H Zhou, S Gao, N N Nguyen, M Fan, J Jin, B Liu, L Zhao, G Xiong, M Tan, S Li, L Wong. Stringent Homology-based Prediction of H. sapiens-M. tuberculosis H37Rv Protein-Protein Interactions. Biology Direct, 9(5):1-52 (2014). Cited 50 times according to Google Scholar [9]

References

Sources

  • Bing Liu Archived 2020-05-18 at the Wayback Machine, personal site / Research Assistant Professor, Computational & Systems Biology Department, School of Medicine, University of Pittsburgh
  • Bing Liu Archived 2022-11-06 at the Wayback Machine, Ph.D., Research Assistant Professor, Ph.D. in Computational Systems Biology, National U of Singapore
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