Beaded septum sign

Beaded septum sign is a radiologic sign seen on chest computed tomography (CT).[1] It is characterized by irregular, nodular thickening of the interlobular septa, giving them a “beaded” or “string-of-pearls” appearance.[2]

The sign is classically associated with pulmonary lymphangitic carcinomatosis, but may also be encountered in other malignant and non-malignant conditions affecting the pulmonary lymphatics.[1]

References

  1. 1 2 Lee, Kyung Soo; Han, Joungho; Chung, Man Pyo; Jeong, Yeon Joo (2014). "Beaded Septum Sign". Radiology Illustrated: Chest Radiology. Springer: 49–50. doi:10.1007/978-3-642-37096-0_4. Retrieved 3 January 2026.
  2. ↑ Hansell, David M.; Bankier, Alexander A.; MacMahon, Heber; McLoud, Theresa C.; Müller, Nestor L.; Remy, Jacques (March 2008). "Fleischner Society: Glossary of Terms for Thoracic Imaging". Radiology. 246 (3): 697–722. doi:10.1148/radiol.2462070712. ISSN 0033-8419. Retrieved 3 January 2026.
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