Acetophenone carboxylase

Acetophenone carboxylase
Identifiers
EC no.6.4.1.8
Databases
BRENDAenzyme data
ExPASyNiceZyme view
KEGGenzyme entry
MetaCycmetabolic pathway
Rheareactions
PDB structuresRCSB PDB PDBe PDBsum
Search
PMCarticles
PubMedarticles
NCBIproteins

Acetophenone carboxylase (EC 6.4.1.8) is an enzyme with systematic name acetophenone:carbon-dioxide ligase (ADP-forming).[1] This enzyme catalyses the following chemical reaction

2 ATP + acetophenone + HCO3− + H2O + H+ 2 ADP + 2 phosphate + 3-oxo-3-phenylpropanoate

The enzyme is involved in anaerobic degradation of ethylbenzene.

References

  1. ↑ Jobst B, Schühle K, Linne U, Heider J (March 2010). "ATP-dependent carboxylation of acetophenone by a novel type of carboxylase". Journal of Bacteriology. 192 (5): 1387–94. doi:10.1128/jb.01423-09. PMC 2820866. PMID 20047908.