ALG10B

ALG10B
Identifiers
Aliases	ALG10B, ALG10, KCR1, alpha-1,2-glucosyltransferase, ALG10 alpha-1,2-glucosyltransferase B
External IDs	OMIM: 603313; MGI: 2146159; GeneCards: ALG10B
Enzyme activity
Gene location (Human)
Chr.	Chromosome 12 (human)
End	38,329,721 bp
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)
End	90,117,674 bp
RNA expression pattern
	Top expressed in
	Achilles tendon; ; retinal pigment epithelium; ; tibia; ; testicle; ; germinal epithelium; ; gonad; ; ventricular zone; ; ganglionic eminence; ; mucosa of paranasal sinus; ; endometrium;
	Top expressed in
	hand; ; secondary oocyte; ; superior cervical ganglion; ; primary oocyte; ; atrioventricular valve; ; otolith organ; ; trigeminal ganglion; ; utricle; ; endocardial cushion; ; medial ganglionic eminence;
	More reference expression data
	n/a
Gene ontology
Molecular function	dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity; glycosyltransferase activity; transferase activity; dolichyl pyrophosphate Glc2Man9GlcNAc2 alpha-1,2-glucosyltransferase activity;
Cellular component	integral component of membrane; plasma membrane; endoplasmic reticulum membrane; membrane; endoplasmic reticulum;
Biological process	dolichol-linked oligosaccharide biosynthetic process; protein glycosylation; positive regulation of protein glycosylation; positive regulation of inward rectifier potassium channel activity;
	Sources:Amigo / QuickGO
Orthologs
Databases	NCBI: entry; OMA: entry
	144245
	380959
	ENSG00000175548
	ENSMUSG00000075470
	Q5I7T1
	Q3UGP8
	NM_001013620; NM_001308340
	NM_001033441
	NP_001013642; NP_001295269
	NP_001028613
	Wikidata
View/Edit Human	View/Edit Mouse

Alpha-1,2-glucosyltransferase ALG10-B is an enzyme that in humans is encoded by the ALG10B gene.^[5] It is a member of the Dolichyl-P-Glc:Glc2Man9GlcNAc2-PP-dolichol alpha-1,2-glucosyltransferase class of enzymes. It has ubiquitous expression in 27 tissues.^[6]

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000175548 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000075470 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ UniProt ID: Q5I7T1. Retrieved 30 November 2019
↑ "Entrez Gene: ALG10B ALG10 alpha-1,2-glucosyltransferase B". Retrieved 30 November 2019.

[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000175548 – Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000075470 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[5] UniProt ID: Q5I7T1. Retrieved 30 November 2019

[entrez-6] "Entrez Gene: ALG10B ALG10 alpha-1,2-glucosyltransferase B". Retrieved 30 November 2019.

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