Aminoadipate-semialdehyde dehydrogenase

AASDH
Identifiers
Aliases	AASDH, ACSF4, LYS2, NRPS1098, NRPS998, aminoadipate-semialdehyde dehydrogenase
External IDs	OMIM: 614365; MGI: 2442517; GeneCards: AASDH
Enzyme activity
Gene location (Human)
Chr.	Chromosome 4 (human)
End	56,387,508 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	77,053,361 bp
RNA expression pattern
	Top expressed in
	pancreatic ductal cell; ; nipple; ; corpus epididymis; ; gonad; ; testicle; ; caput epididymis; ; renal medulla; ; oocyte; ; tail of epididymis; ; mucosa of ileum;
	Top expressed in
	Paneth cell; ; otolith organ; ; utricle; ; conjunctival fornix; ; fossa; ; ciliary body; ; iris; ; spermatocyte; ; condyle; ; hand;
	More reference expression data
	n/a
Orthologs
Databases	NCBI: entry; OMA: entry
	132949
	231326
	ENSG00000157426
	ENSMUSG00000055923
	Q4L235
	Q80WC9
NM_001286668; NM_001286669; NM_001286670; NM_001286671; NM_001286672;
	NM_181806; NM_001323890; NM_001323892; NM_001323893; NM_001323899
	NM_173765; NM_001377004
NP_001273597; NP_001273598; NP_001273599; NP_001273600; NP_001273601;
	NP_001310819; NP_001310821; NP_001310822; NP_001310828; NP_861522
	NP_776126; NP_001363933
	Wikidata
View/Edit Human	View/Edit Mouse

Aminoadipate-semialdehyde dehydrogenase is a protein that in humans is encoded by the AASDH gene.^[5]

Function

This gene encodes a member of the non-ribosome peptide synthetase (NRPS) enzyme family. The encoded protein contains an AMP-binding domain, PP-binding (phosphopantetheine, or pantetheine 4'phosphate-binding) domain and the Pyrrolo-quinoline quinon (PQQ) binding domain. The protein is expressed in several adult tissues.

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000157426 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000055923 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Entrez Gene: Aminoadipate-semialdehyde dehydrogenase". Retrieved 2017-01-02.

Function

References

Further reading