5-aminovalerate transaminase
| 5-aminovalerate transaminase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.6.1.48 | ||||||||
| CAS no. | 37277-97-7 | ||||||||
| Databases | |||||||||
| BRENDA | enzyme data | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | enzyme entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| Rhea | reactions | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
5-aminovalerate transaminase (EC 2.6.1.48) is a pyridoxal phosphate-dependent enzyme that catalyzes the chemical reaction
The two substrates of this enzyme characterised from Pseudomonas bacteria are δ-aminovaleric acid and α-ketoglutaric acid. Its products are 5-oxopentanoic acid and L-glutamic acid.[1]
This enzyme is a transferase, specifically a transaminase, which transfer nitrogenous groups. The systematic name of this enzyme class is 5-aminopentanoate:2-oxoglutarate aminotransferase. Other names in common use include 5-aminovalerate aminotransferase, delta-aminovalerate aminotransferase, and delta-aminovalerate transaminase. It participates in lysine degradation.[2]
References
- ↑ Ichihara A, Ichihara EA, Suda M (1960). "Metabolism of L-lysine by bacterial enzymes. IV. delta-Aminovaleric acid-glutamic acid transaminase". J. Biochem. 48 (3). Tokyo: 412–420. doi:10.1093/oxfordjournals.jbchem.a127187.
- ↑ Enzyme 2.6.1.48 at KEGG Pathway Database.