4-Sulfomuconolactone hydrolase
| 4-sulfomuconolactone hydrolase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 3.1.1.92 | ||||||||
| Databases | |||||||||
| BRENDA | enzyme data | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | enzyme entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| Rhea | reactions | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
The enzyme 4-sulfomuconolactone hydrolase (EC 3.1.1.92; systematic name 4-sulfomuconolactone sulfohydrolase)[1] catalyses the chemical reaction:
The enzyme characterised from Hydrogenophaga intermedia and Agrobacterium radiobacter S2 hydrolyses the 4-sulfomuconolactone to maleylacetic acid and sulfurous acid. The reaction is part of the degradation pathway for 3,4-dihydroxybenzenesulfonic acid in these bacteria.[2] The bacterial co-culture is able to metabolise other compounds such as 4-aminobenzenesulfonic acid.[3]
References
- ↑ Enzyme 3.1.1.92 at KEGG Pathway Database.
- ↑ Halak S, Basta T, Bürger S, Contzen M, Wray V, Pieper DH, Stolz A (October 2007). "4-sulfomuconolactone hydrolases from Hydrogenophaga intermedia S1 and Agrobacterium radiobacter S2" (PDF). Journal of Bacteriology. 189 (19): 6998–7006. doi:10.1128/jb.00611-07. PMC 2045233. PMID 17660282.
- ↑ Kim, Kangsan; Gan, Han Ming (2017). "A glimpse into the genetic basis of symbiosis between Hydrogenophaga and their helper strains in the biodegradation of 4-aminobenzenesulfonate". Journal of Genomics. 5: 77–82. doi:10.7150/jgen.20216. PMC 5535693. PMID 28775791.
External links
- 4-sulfomuconolactone+hydrolase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
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