3-phosphoglycerate phosphatase
| 3-phosphoglycerate phosphatase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 3.1.3.38 | ||||||||
| CAS no. | 62213-13-2 | ||||||||
| Databases | |||||||||
| BRENDA | enzyme data | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | enzyme entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| Rhea | reactions | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
The enzyme 3-phosphoglycerate phosphatase (EC 3.1.3.38) catalyzes the reaction
The enzyme characterised from sugarcane and rice hydrolyses 3-phospho-D-glyceric acid to D-glyceric acid and orthophosphate.[1][2] The reaction is part of the biosynthesis of the amino acid serine.[3] The enzyme has also been studied as part of a sequence to manufacture fructose from starch waste products.[4]
This enzyme is a hydrolase, specifically one acting on phosphoric monoester bonds. The systematic name is D-glycerate-3-phosphate phosphohydrolase. Other names in common use include D-3-Phosphoglycerate phosphatase, and 3-PGA phosphatase.[5]
References
- ↑ Randall DD, Tolbert NE (1971). "3-Phosphoglycerate phosphatase in plants. I. Isolation and characterization from sugarcane leaves". J. Biol. Chem. 246 (17): 5510–7. doi:10.1016/S0021-9258(18)61935-0. PMID 10970181.
- ↑ Villareal, Ruth M.; Juliano, Bienvenido O. (1977). "Some Properties of 3-Phosphoglycerate Phosphatase from Developing Rice Grain". Plant Physiology. 59 (2): 134–138. doi:10.1104/pp.59.2.134. PMC 542350. PMID 16659802.
- ↑ Wang, Mengyao; Tabeta, Hiromitsu; Ohtaka, Kinuka; et al. (2024). "The phosphorylated pathway of serine biosynthesis affects sperm, embryo, and sporophyte development, and metabolism in Marchantia polymorpha". Communications Biology. 7 (1) 102. doi:10.1038/s42003-023-05746-6. PMC 10808223. PMID 38267515.
- ↑ Marafi, Rawia; Batchu, Sai Praneet; Venkitasubramanian, Padmesh; Hagberg, Erik C.; Broadbelt, Linda J.; Tyo, Keith E. J. (2026). "Kinetic Modeling of Phosphate-Based Enzyme Cascade for the Production of Fructose from Starch". Chemfoodchem e70024. doi:10.1002/cfch.70024.
- ↑ Enzyme 3.1.3.38 at KEGG Pathway Database.
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