3-hydroxypropionate dehydrogenase
| 3-hydroxypropionate dehydrogenase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.1.1.59 | ||||||||
| CAS no. | 9028-59-5 | ||||||||
| Databases | |||||||||
| BRENDA | enzyme data | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | enzyme entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| Rhea | reactions | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In enzymology, a 3-hydroxypropionate dehydrogenase (EC 1.1.1.59) is an enzyme that catalyzes the chemical reaction
The two substrates of this enzyme are 3-hydroxypropionic acid and oxidised nicotinamide adenine dinucleotide (NAD+). Its products are 3-oxopropanoic acid, reduced NADH, and a proton.[1][2]
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 3-hydroxypropanoate:NAD+ oxidoreductase. This enzyme participates in beta-alanine metabolism and propanoate metabolism.
See also
- 3-hydroxypropionate dehydrogenase (NADP+) which catalyses the same reaction with an alternative cofactor
References
- ↑ Enzyme 1.1.1.59 at KEGG Pathway Database.
- ↑ Den H, Robinson WG, Coon MJ (1959). "Enzymatic conversion of beta-hydroxypropionate to malonic semialdehyde". J. Biol. Chem. 234 (7): 1666–1671. doi:10.1016/S0021-9258(18)69904-1. PMID 13672942.