2,3-bisphosphoglycerate 3-phosphatase
| 2,3-bisphosphoglycerate 3-phosphatase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 3.1.3.80 | ||||||||
| Databases | |||||||||
| BRENDA | enzyme data | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | enzyme entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| Rhea | reactions | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
2,3-Bisphosphoglycerate 3-phosphatase (EC 3.1.3.80, MIPP1, 2,3-BPG 3-phosphatase) is an enzyme with systematic name 2,3-bisphospho-D-glycerate 3-phosphohydrolase.[1] It catalyses the following reaction:
The enzyme characterised from Dictyostelium, birds, and mammals hydrolyses 2,3-bisphospho-D-glyceric acid to 2-phospho-D-glyceric acid and orthophosphate (Pi). The reaction is a shortcut in the Luebering-Rapoport pathway.[2][3]
References
- ↑ Enzyme 3.1.3.80 at KEGG Pathway Database.
- ↑ Cho J, King JS, Qian X, Harwood AJ, Shears SB (April 2008). "Dephosphorylation of 2,3-bisphosphoglycerate by MIPP expands the regulatory capacity of the Rapoport-Luebering glycolytic shunt". Proceedings of the National Academy of Sciences of the United States of America. 105 (16): 5998–6003. Bibcode:2008PNAS..105.5998C. doi:10.1073/pnas.0710980105. PMC 2329705. PMID 18413611.
- ↑ Schomburg, Dietmar; Schomburg, Ida (2013). "2,3-bisphosphoglycerate 3-phosphatase 3.1.3.80". Class 2–3.2 Transferases, Hydrolases. pp. 484–487. doi:10.1007/978-3-642-36240-8_110. ISBN 978-3-642-36239-2.
External links
- 2,3-bisphosphoglycerate+3-phosphatase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
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