121st Brigade
121st Brigade may refer to:
China
- 121st Brigade, Republic of China; see January 28 incident order of battle
India
- 121 (Independent) Infantry Brigade, part of 8th Infantry Division (India)
Soviet Union
- 121st Guards Artillery Brigade
- 121st High-Power Howitzer Artillery Brigade, part of 5th Shock Army
- 121st Separate Tank Brigade, part of 65th Army (Soviet Union)