+ electron
acceptor
(R)-pantolactone dehydrogenase (flavin)
| (R)-pantolactone dehydrogenase (flavin) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.1.99.27 | ||||||||
| CAS no. | 140879-14-7 | ||||||||
| Databases | |||||||||
| BRENDA | enzyme data | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | enzyme entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| Rhea | reactions | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In enzymology, (R)-pantolactone dehydrogenase (flavin) (EC 1.1.99.27) is an enzyme that catalyzes the chemical reaction
-Pantolacton.svg.png)
(R)-pantolactone
2-dehydropantolactone
+ reduced
acceptor
acceptor
The two substrates of this enzyme are (R)-pantolactone and an electron acceptor. Its products are 2-dehydropantolactone and the corresponding reduced acceptor.[1][2]
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with other acceptors. The systematic name of this enzyme class is (R)-pantolactone:acceptor oxidoreductase (flavin-containing). Other names in common use include 2-dehydropantolactone reductase (flavin), 2-dehydropantoyl-lactone reductase (flavin), and (R)-pantoyllactone dehydrogenase (flavin).
References
- ↑ Enzyme 1.1.99.27 at KEGG Pathway Database.
- ↑ Kataoka M, Shimizu S, Yamada H (1992). "Purification and characterization of a novel FMN-dependent enzyme Membrane-bound L-(+)-pantoyl lactone dehydrogenase from Nocardia asteroides". Eur. J. Biochem. 204 (2): 799–806. doi:10.1111/j.1432-1033.1992.tb16698.x. PMID 1541293.