(Iso)eugenol O-methyltransferase

(iso)eugenol O-methyltransferase
Identifiers
EC no.2.1.1.146
CAS no.191744-33-9
Databases
BRENDAenzyme data
ExPASyNiceZyme view
KEGGenzyme entry
MetaCycmetabolic pathway
Rheareactions
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
Search
PMCarticles
PubMedarticles
NCBIproteins

(Iso)eugenol O-methyltransferase (EC 2.1.1.146) is an enzyme that catalyzes the chemical reaction

+ SAM
 
 
 
 
Rightward reaction arrow
 
 
 
+ SAH
 

This is a methylation reaction in which isoeugenol is converted to its di-ether, methyl isoeugenol. The methyl group comes from the cofactor, S-adenosyl methionine (SAM), which becomes S-adenosyl-L-homocysteine (SAH). The enzyme was characterised from Clarkia breweri.[1][2]

This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:isoeugenol O-methyltransferase. It also acts on eugenol[3]

References

  1. ↑ Wang J, Pichersky E (1998). "Characterization of S-adenosyl-L-methionine:(iso)eugenol O-methyltransferase involved in floral scent production in Clarkia breweri". Arch. Biochem. Biophys. 349 (1): 153–60. doi:10.1006/abbi.1997.0452. PMID 9439593.
  2. ↑ JP, Pichersky E; Lavid, N; Zubieta, C; Chen, F; Beuerle, T; Lewinsohn, E; Noel, JP; Pichersky, E (2002). "Characterization of phenylpropene O-methyltransferases from sweet basil: facile change of substrate specificity and convergent evolution within a plant O-methyltransferase family". Plant Cell. 14 (2): 505–19. doi:10.1105/tpc.010327. PMC 152928. PMID 11884690.
  3. ↑ Enzyme 2.1.1.146 at KEGG Pathway Database.